OB/GYN PICOs:

In patients in labor, is listening to music as a non-pharmaceutical treatment method effective in decreasing pain and discomfort during labor?

In women with a previous c-section, does vaginal delivery lead to more complications for the mother when compared to a repeat c-section?

In patients with ectopic pregnancy who are hemodynamically stable, is methotrexate more effective/prefered in safer termination of pregnancy when compared to expectant management?

Psychiatry PICOs:

In patients with depression, is the combination of cognitive behavioral therapy with SSRIs more effective in reducing suicide ideation compared to SSRIs/antidepressants alone?

In children with autism spectrum disorder, does limiting screen time reduce/improve symptoms of autism compared to children with more screen time?

In adults with depression, what is the comparative efficacy of St. John’s Wort versus SSRIs in terms of symptom reduction and overall treatment outcomes?

Family Medicine PICO:

In adults with a history of recurrent kidney stones, does increased fluid intake compared to standard fluid intake decrease recurrence rate of kidney stones?

In patients with osteoarthritis, does curcumin (turmeric) supplementation reduce symptoms such as pain and inflammation compared to a placebo or NSAIDs?

In adults with hypertension, does mindfulness-based stress reduction programs/interventions, compared to standard care or no intervention result in reduction in blood pressure?

Emergency Medicine PICOs:

In adults with hyperuricemia at risk for gout, does oral vitamin C supplementation reduce serum uric acid levels and decrease the risk of gout compared to no supplementation?

In adults presenting to the emergency department with suspected fractures, does point-of-care ultrasound offer comparable diagnostic accuracy and a quicker diagnosis compared to traditional X-ray imaging?

In adolescents, do school based mental health services/counseling lead to improved outcomes in anxiety and depression compared to no mental health services in school?

MINI-CAT:

Spring 2024: In patients experiencing insomnia or sleep disturbances, does meditation improve sleep quality and reduce sleep disturbances compared to not practicing meditation/other treatments?

Summer 2024: In adults with persistent low back pain, does practicing yoga compared to physical therapy lead to reduction in pain intensity and improve physical function?  

Fall 2024 CAT topic: In stroke patients with upper limb motor impairments, how does virtual reality-based therapy compared to standard physical therapy or no physical therapy affect limb motor function?